Introduction. Evaluating functional state of workers engaged intohazardous work conditions, researchers use not only traditional objective study methods, but also subjective parameters including sociologic polls of workers, with subjective evaluation of working process character, fatigue degree, time dimension, lifestyle, etc.
Objective. To compare informativeness of integral criteria of work capacity according to WAI (Work Ability Index) questionnaires with other methods traditionally used in occupational physiology.
Materials and methods. Th e study covered workers of plate rolling production in JSC «Arselor Mittal-Temirtau». Physiologic and statistical methods were used.
Results. Comparative analysis of work capacity index via WAI with other methods traditionally used in occupational physiology demonstrated that WAI dynamics completely corresponds to central nervous system capacity dynamics, partially corresponds to cardiovascular functional strain dynamics, minimally corresponds to neuromuscular apparatus activity. WAI index can indirectly outline body resistance level assessed by transitory disablement morbidity parameters.
Conclusions. Work capacity index by WAI could be directly extrapolated to levels of central nervous system strain and workers’ resistance (evaluated by transitory disablement morbidity), because the correlation dependences revealed completely correspond to dynamics of work capacity index by WAI. Such correspondence was not seen for cardiovascular system and neuromuscular apparatus.

Introduction. Coal dust and coal fi ring products contain large amounts of carcinogenic chemicals (specifically benz[a]pyrene) that are different in influence on workers of coal mines and thermal power plants. Specific immune reactions to benz[a]pyrene therefore in these categories of workers can have specific features.
Objective. To reveal features of antibodies specifi c to benz[a]pyrene formation in workers of coal mines and thermal power plants.
Materials and methods. The study covered A and G class antibodies against benz[a]pyrene (IgA-Bp and IgG-Bp) in serum of 705 males: 213 donors of Kemerovo blood transfusion center (group 1, reference); 293 miners(group 2) and 199 thermal power plant workers (group 3). Benz[a]pyrene conjugate with bovine serum albumin as an adsorbed antigen was subjected to immune-enzyme assay.
Results. IgA-Bp levels in the miners (Me = 2.7) did not differ from those in the reference group (Me = 2.9), but in the thermal power plant workers (Me = 3.7) were reliably higher than those in healthy men and in the miners (p<0.0001). Levels of IgG-Bp in the miners (Me = 5.0) appeared to be lower than those in the reference group (Me = 6.4; (p = 0.05). IgG-Bb level in the thermal power plantworkers (Me = 7.4) exceeded the parameters in the healthy donors and the miners (p<0.0001). Non-industrial factors (age and smoking) appeared tohave no influence on specific immune reactions against benz[a]pyrene in the miners and the thermal power plant workers.
Conclusions. Specific immune reactions against benz[a]pyrene in the miners and the thermal power plant workers are characterized by peculiarities: the miners demonstrate lower levels of class A serum antibodies to benz[a]pyrene; the thermal power plant workers present increased serum levels of class G antibodies to benz[a]pyrene. These peculiarities result from only the occupational features, but do not depend on such factors as age, smoking and length of service at hazardous production. It is expedient to study specific immune reactions to benz[a]pyrene in workers of coal mines and thermal power plants, to evaluate individual oncologic risk and if malignancies occur.

Introduction. Health preservation for public health care workers, by means of psycho-rehabilitation programs managing stress in medical establishments, is a topical medical, psychologic and economic task.
Objective. To study levels of emotional exhaustion, depersonalization and personal achievements reduction as psychologic burnout factors in workers of primary health care, depending on position and educational level, with specification of psychologic rehabilitation program and evaluation of its efficiency.
Materials and methods. The study covered 137 female medical workers of outpatient departments in Moscow, with emotional burnout syndrome and length of service at least 5 years. Emotional burnout syndrome was assessed via a questionnaire «Occupational burnout» including 3 scales: «Emotional exhaustion» (1), «Depersonalization» (2) and «Personal achievements reduction» (3). 3 groups of the examinees were identified: group 1 — senior officers (15), group 2 — doctors (40), group 3 — nurses and paramedical personnel (82). All the examinees underwent 8 weeks of psychologic rehabilitation based on training of stress-resistance, personality development and relaxation methods.
Results. Groups 1 and 2 demonstrated medium (scales 1 and 3) and high (scale 2) levels of emotional burnout syndrome, and the group 3 presented medium (scale 3) and low (scales 1 and 2) levels. All the groups responded positively on psychologic rehabilitation that decreased emotional exhaustion, increased responsibility for daily duties, improved and stabilized self-esteem.
Conclusions. Manifestations of emotional burnout syndrome depend on peculiarities of medical workers’ occupational activities, position and educational level. Emotional exhaustion and depersonalization are more marked in senior officers and in doctors, than in nurses and paramedical personnel. Self-evaluation of occupational competence and activities is the same among all categoriesof the medical workers. psychologic rehabilitation enables to decrease symptoms of emotional burnout syndrome and is an important component of programs preserving working potential of medical establishments.

Introduction. Reproductive system disorders, according to many authors, are among integral indicators of sanitary hygienic ill-being of territories and reflect an environmental aggression degree. Ecologic and hygienic studies of reproductive health, conducted in some entities of Russian Federation, demonstrated that environmental substances with mutagenic and reproductivity compromising activity increase prevalence of congenital anomalies 1.4–1.8 times over the reference values. During 2000–2010, prevalence of congenital anomalies in Russia varies within 30.0–30.9‰.
Objective. To reveal epidemiologic features of congenital anomalies development in ecologic situation formed by various economy branches.
Materials and methods. Ecologic and hygienic evaluation covered reproductive health of women residents in ecologically unfavorable regions. Th e work contained also information on sanitary and hygienic state of environment and public health state, taken from offi cial and public materials of Rospotrebnadzor and Health Ministry of Bashkortostan Republic over 2009–2016.
Results. Congenital anomalies in fetus increased. In 2015, 21.4 congenital anomalies were registered per 1,000 children aged under 1 year. High levels of congenital anomalies over 2000–2015 were seen in regions of ores mining and extraction, with high content of heavy metals affecting reproductivity (copper, chromium, zinc, cadmium, cobalt, nickel, lead, mercury, manganese, etc.) — in these regions, incidence of congenital anomalies was 3.78 times higher than general level in the Republic.
Conclusions. Congenital anomalies levels obviously characterize reproductiverisk of ecologic situation, can be a criterion of sanitary epidemiologic ill-being and serve as an indicator in social hygienic monitoring.

Introduction. Work of locomotive crew members (engine drivers and engine driver assistants) in railway transport is associated with exposure to complex of occupational hazards including psychoemotional stress and shiftwork (with night shifts) along with noise and vibration.
Objective. To study influence of shift work (with irregular alternation of day and night shifts) on biorhythms disturbances in locomotive crew workers.
Materials and methods. Polls, simulators of occupational activities with training complex «Cabin of engine driver EP1M», daily monitoring of blood pressure, statistic data processing by SPSS–20 software.
Results. Findings are that 953 locomotive crew workers (94%) experienced sensations of temporary disorientation, slight dizziness, sleepiness, interpreted as monotony and sensor deprivation. 61% of the examinees demonstrated frustration signs, in 30% of the cases there were certain manifestations of mental ill-being — irritability, fatigue, weariness, absent-mindedness, anxiety; 27.2% of the testees experiences various sleep disorders; 13.8% of the workers complained of «light sleep», 2% of those — restless sleep, 0.6% — sleeplessness. In occupationally related biorhythms disturbance, the body undergoes occupational adaptation, with partial transformation for atypical schedule of sleep and wakefulness.
Results. To preserve health, efforts should be aimed at adaptation to shifted occupational activities with safe adaptogenic medications, low-caloric diet for individuals working at irregular shifts, create conditions for adequate physical activity of the workers between shifts. Necessities also are individual norms for blood pressure parameters in engine drivers with night shiftwork, specification of antihypertensive treatment for patients with irregular shifted work.

Introduction. The study is aimed to determine possible use of vocal signal analysis for diagnosis of functional states in air traffic control operators, with justifying selection of informative parameters of intonation structure of speech.
Materials and methods. Experiments on semi-natural simulator complex with participation of 16 air traffic male dispatchers modelled occupational activity of air traffic dispatcher with moderate (6 aircrafts controlled) and intense (7–12 aircrafts controlled) work load. Duration of simulated working shiftwas 6 hours. Registration covered characteristics of main vocal tone of the examinees, with calculation of 8 jitter-factors that portrayed mirco-changes of main vocal tone curve and 2 tremor indices disclosing periodic waves of 4–16 Hz in main vocal tone curve. Functional state of the dispatchers was assessed via cardiac rhythm parameters. Reliability and work capacity of the dispatchers corresponded to correct radio traffi c, changes in threshold of reception and transfer of aircrafts in number of allowable dangerous approach of aircrafts, time to detection of input aircraft’s deviation from preset flight line.
Results and discussion. According to analysis of the experiments results, some parameters of the main vocal tone carried significant changes both in first (simulated moderate work load) and second (simulated intense work load) experimental series.
The data obtained prove lower level of psychic regulation of the dispatchers’ occupational activity during 3rd to 5thhours of “working shift” in the first experimental series and from 2nd to 4thhours of the second experimental series, due to decreased psychophysiologic resources and developing fatigue.
Conclusion. Studies of changes in indicators of intonation structure of speech in occupational activity of air traffic dispatchers demonstrated that using such indicators provides adequate diagnosis of the functional state. The most informative indicators are average value, histogram asymmetry and excessive frequency of main vocal tone, duration of pauses between words of the dispatchers’ commands and fi ft h jitter-factor.

The authors analyzed pathogenetic, clinical and epidemiologic features of occupational kidney disorders due to physical and biologic factors, and problems of diagnosis and prevention. The review presented covers national and foreign literature data on occupational diseases of kidneys and urinary tract due to contact with various occupational factors.

The article presents evolutionary changes in occupationally related nonspecific and specific hematologic syndromes, occupational chronic intoxications and blood diseases due to contact with various occupational hazards mostly hematotropic ones, depending on length of service. The presented hematologic characteristics cover specific occupationally related microelement disorders and occupational chronic intoxications during primary diagnosis and in post-contact period. Findings areless occupational chronic chemical intoxications and blood disorders due to hematotropic occupational influences.

The authors specified a method to evaluate informativeness of laboratory biomarkers for early diagnosis of occupational factors’ influence on human body: calculation of diagnostic sensitivity, prenosologic importance, pathognomonicity in the case if average laboratory values are within the reference intervals. The method suggested enables considerable decrease errors in calculation of diagnostic characteristics.

The article presents results of assessing lung parenchyma density within X-ray diagnostic pattern “Opal glass” in patients with changes characteristic for occupational hypersensitivity pneumonitis(60 patients) and interstitial pneumonia (65 patients of reference group) vs. reference group (70 individuals), by modified method of X-ray computer tomography of high resolution. Quantitative characteristics as native parameter (HU units), density gradient (IDG), with consideration of homogeneity degree of the evaluated zone by SD value enabled considerable objectification of the changes direction in diagnostic monitoring of the studied lung disorders.

The article presents results of evaluating efficiency of special cooling liquid influence on heat state of athletes at high temperatures. The study covered 7 male athletes of cyclic sports, with sport rank at least 1 adult, average age 19.29±1.80 years. All the athletes underwent double examination including: anamnesis and complaints records, doctor’s examination, subjective evaluation of heat sensations, weight measurements, thermometry (tympanic, sublingual, rectal and skin (in 5 points)), ergospirometric stress testing. Changes in the athletes’ heat state were evaluated via dynamics of weighted average skin temperature and rectal temperature. Moreover, subjective evaluation of heat sensations was considered. Efficiency of the cooling liquid was assessed via dynamics of exercises performance time, maximal oxygen consumption and anaerobic metabolism threshold. The cooling liquid use appeared to be expedientin sport teams of summer sports for specific exertion after individual tests for adverse allergic reactions.